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CDC guidance

Travel health notices explained

Alongside the State Department's security advisories, the CDC maintains its own travel health notice system focused purely on disease risk. The two systems are independent — a destination can be perfectly safe from a security standpoint and still carry an active health notice, or vice versa.

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What CDC travel health notices are

The Centers for Disease Control and Prevention (CDC) publishes destination-level health guidance and issues travel health notices when there's a specific disease risk travelers should know about — a disease outbreak, an environmental hazard, or a health-related event like a natural disaster. Notices are published on the CDC's Travelers' Health site, organized by destination.

The four notice levels

  • Level 1 — Practice usual precautions. Follow routine travel health guidance; no unusual outbreak is active.
  • Level 2 — Practice enhanced precautions. A specific disease risk is present; the CDC recommends targeted precautions for certain travelers (for example, additional vaccines or avoiding specific activities).
  • Level 3 — Avoid nonessential travel. An outbreak or health risk is significant enough that the CDC recommends postponing non-essential trips to the affected area.
  • Level 4 — Avoid all travel. Reserved for the most severe situations, such as a widespread outbreak with limited local healthcare capacity.

Notices are usually specific to a disease and sometimes to a region within a country, so always read the notice text rather than just the level number.

Vaccines and routine care

The CDC also maintains standard vaccine recommendations for each destination, separate from active outbreak notices. Depending on where you're headed, you may see recommendations that fall into a few categories:

  • Routine vaccines you should already be current on regardless of travel (MMR, tetanus, flu, etc.).
  • Recommended vaccines specific to the region (such as hepatitis A/B, typhoid, or yellow fever in some countries).
  • Required vaccines that some countries mandate for entry, most commonly yellow fever certificates for travel from or through certain regions.

A travel medicine clinic or your primary care provider can review your itinerary and recommend a specific vaccine and medication plan — ideally 4 to 6 weeks before departure, since some vaccines require multiple doses or need time to take effect.

Before you go

  • Check the CDC's destination page for your country (and any transit countries) for current notices.
  • Confirm whether any vaccines are required for entry, not just recommended.
  • Pack a basic health kit: prescription medications in original packaging, a copy of prescriptions, pain relievers, rehydration salts, and any destination-specific items (like antimalarials, if recommended).
  • Check whether your health insurance covers care abroad — most U.S. plans, including Medicare, generally do not.

While you're traveling

  • Stick to bottled or treated water in destinations where tap water isn't recommended.
  • Use insect repellent and protective clothing in regions with mosquito-borne illness risk.
  • Know the location and reputation of the nearest hospital or clinic to where you're staying.
  • If you feel unwell during or shortly after a trip, tell any treating doctor exactly where you traveled — it can be the key clue in diagnosis.

Check before you book

Review current notices at the CDC's Travelers' Health site (cdc.gov/travel) for every country on your itinerary, including layovers. Health notices can change faster than a printed guide.

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